NEW SERVICE FOR PROSPECTIVE GRADUATE STUDENTS
Register now with the Fullerton VIP GradConnect Service for customized program information and a personalized experience as you begin your journey toward achieving your graduate degree.
Department of Chemistry & Biochemistry Faculty
Dr. Nicholas Salzameda
Assistant Professor Organic & Bioorganic Chemistry
Phone: (657) 278-3594
Lab: DBH-182/183
Phone:(657) 278-3913/2596
Email: nsalzameda@fullerton.edu
Teaching
CHEM 301A Organic Chemistry
CHEM 302 Organic Chemistry Laboratory
Education
Postdoctoral, The Scripps Research Institute, La Jolla, CA (Professor Kim Janda)
Ph.D. University of Nevada, Reno (Professor David Lightner)
B.A. University of San Diego, California
Research Interests
We are involved in two areas of research: the synthesis of novel peptide catalysts for asymmetric carbon-carbon bond forming reactions and the discovery of biologically active molecules for disruption of protein-protein interactions, focusing on targets related to human health. Both of these research objectives are centered on solid phase reaction methodology.
Salzameda Group Activities
January 2012: Salzameda Group undergraduate students Allia Fawaz and Alex Burtea present their research at the 24th Annual CSU Program for Education and Research in Biotechnology in San Jose, California.
December 2011: Undergraduates Cheryl Tjandra and Roxanne Maniquis join the Salzameda Group.
March 2011: Salzameda Group undergraduate students, Vince Vu, Allia Fawaz, Omran Karmach and Alex Burtea present their research at the ACS National Meeting:
- Alex Burtea and Allia Fawaz, poster title: "Discovery and development of small molecule inhibitors for the botulinum neurotoxin E protease"
- Omar Karmach and Vince Vu, poster title: "Development and application of peptide catalysts for the asymmetric Michael addition"
Recent Publications
Lowery, C. A.; Salzameda, N. T.; Sawada, D.; Kaufmann, G. F.; Janda, K. D. “Medicinal Chemistry as a Conduit for the Modulation of Quorum Sensing” J. Med. Chem. Accepted (2010)
Eubanks L.M.; Silhar, P, Salzameda, N.T.; Zakhari J. S.; Xiaochuan F.; Barbieri, J. T.; Shoemaker, C. B.; Hixon, M. S.; Janda, K. D. “Identification of a Natural Product Antagonist against the Botulinum Neurotoxin Light Chain Protease” ACS Med. Chem. Lett. In press (2010)
Silhar, P.;Capkova, K.; Salzameda, N.T.; Barbieri, J.T.; Hixon M.S.; Janda, K.D. “Botulinum Neurotoxin Protease A: Discovery of Natural Product Exosite Inhibitor” J. Am. Chem. Soc. 2010, 132, 2868-2869.
Salzameda, N.T.; Barbieri, J.T.; Janda, K.D. “Synthetic Substrate for Application in both High and Low Throughput Assays for Botulinum Neurotoxin B Protease Inhibitors” Bioorg. Med. Chem. Lett., 2009 19, 5848-5850.
Capkova, K.; Salzameda, N. T.; Janda, K. D., “Investigations into Small Molecule Non-peptidic Inhibitors of the Botulinum Neurotoxins” Toxicon, 2009, 54, 575-582.
Salzameda, N. T.; Lightner, D. A., “Intramolecular hydrogen-bonding in C(10) homologated bilirubinoids” Monatsh. Chem., 2007, 138, 237-244.
Salzameda, N. T.; Huggins, M. T.; Lightner, D. A., “Novel N(23)-C(10)-linked linear tetrapyrroles” Tetrahedron, 2006, 62, 9827-9831.
