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Department of Chemistry & Biochemistry Faculty

Dr. Maria Linder
Professor Biochemistry

Office: MH-582K
Phone: (657) 278-2472
Lab: DBH-176/177
Phone: (657) 278-2475/3912
Email: mlinder@fullerton.edu

 

 

Dr. Maria Linder

 

Teaching

CHEM 421 Biological Chemistry
CHEM 422 Biochemistry Laboratory
CHEM 445 Nutritional Biochemistry

Education

Postdoctoral M.I.T. Cambridge, MA
Postdoctoral Harvard Medical School, Boston, MA
Ph.D. Harvard University, Cambridge, MA
B.Sc. Vassar College, Poughkeepsie, NY

Research Interests

An expert on mammalian copper and iron metabolism, Dr. Linder is currently focusing her research on mechanisms of copper transport in the period before and after birth, and on the intestinal absorption and storage of iron, using a broad variety of approaches, from cell culture models, transgenic mice and tracer radioisotopes, to isolation, sequencing and characterization of proteins, as well as si/shRNA manipulation of mRNA/protein expression.

Recent Publications

Linder, M.C. (2010) Nutritional biochemistry of copper, with emphasis on the perinatal period. In: Biochemical Aspects of Human Nutrition (L. Avigliano and L. Rossi, eds.), ISBN 978-81-7895-478-3. Transworld Research Network, Trivandrum, Kerala, India, pp.143-179, in press.

Moriya, M., Ho, Y-H., Grana, A., Nguyen, L., Alvarez, A., Jamil,, R., Ackland, M.L., Michalczyk, A., Hamer, P., Ramos,, D. Kim, S., Mercer, J.F.B., and Linder, M.C. (2008) Copper is taken up efficiently from albumin and alpha-2-macroglobulin by cultured human cells by more than one mechanism.  Am. J. Physiol. (Cell Physiology) 295: 708-721.

Liu, N.M., Lo, L.S.L., Askary, S.H., Jones, L.T., Nguyen, T.T.M., Kidane, T.Z., Goforth, J., Vivas, E., Tsai, M.T., Westbrook, T. and Linder, M.C.  (2007) Transcuprein is a macroglobulin regulated by copper availability. J. Nutritional Biochem. 18: 597-608.

Kidane,, T.Z., Sauble, E. and Linder, M.C. (2006) In three cell types, release of iron from ferritin requires lysosomal activity.  Am. J. Physiol. (Cell Biol.) 291: C445-C455.

Donley, S.A., Ilagan, B.J., Rim, H. and Linder, M.C. (2002)  Copper transport to mammary gland and milk during lactation in rats.  Am. J. Physiol. (Endoc. Metab.), 283, E667-E675.