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Department of Chemistry & Biochemistry Faculty

Dr. Michael Bridges
Assistant Professor Chemistry

Office: MH-534
Phone: (657) 278-2276
Lab: DBH-142/144
Phone: (657) 278-3886
Email: mibridges@fullerton.edu

 


Dr. Michael Bridges

Teaching

CHEM 120B General Chemistry
CHEM 355 Physical Chemistry Laboratory
CHEM 361A/B Introduction to Physical Chemistry

Education

Postdoctoral- University of California, Los Angeles, CA
Ph.D. University of California, Los Angeles, CA
M.Sc. University of British Columbia, Vancouver, Canada
B.Sc. Hon. University of British Columbia, Vancouver, Canada

Research Interests

Dr. Bridges' general research focus is centered on the study of small, intrinsically unstructured proteins and the changes to their motional dynamics upon binding, activation, phosphorylation, etc. Of particular interest is the cytoskeletal regulation protein, stathmin (or oncoprotein-18) - the configurational and dynamical changes it undergoes upon binding to microtubules and free tubulin. The goal is to elucidate the mechanism of microtubule destabilization by Stathmin as a function of phosphorylation level, employing the techniques of side-directed mutagenesis, nitroxice spin labeling of free protein cysteines, and electron paramagnetic resonance (EPR) spectroscopy.