Dr. Madeline Rasche
Professor - Biochemistry
Office MH 504A  
Phone (657) 278-3885  
Lab DBH 178  
Phone (657) 278-2448  
Email merasche@fullerton.edu  

 

 

Teaching
Chem 421  - Biological Chemistry
Chem 423A- General Biochemistry
 
 
 
 
Education
Ph.d 1991 University of California, Riverside, Riverside, CA
B.S. 1985 (Magna cum laude)  Santa Clara University, Santa Clara, CA
 

Research

Study of the biochemical, genetic, and genomic approaches to identify the genes and characterize the enzymes involved in the biosynthetic pathways of selected archaeal coenzymes and potential applications for the modulation of biological methane production and utilization by microorganisms of environmental importance.
Recent Publications  
  1. Testani, J., Dabelic, R. and Rasche, M. E. *.  2006. Chemical reduction of pterins to dihydropterins.  Analytical Biochem . 358:20-24.
  2. Rasche, M. E., and J. G. Ferry. 2005. Molecular Biology of Methanogens and Archaebacteria, p. 237-261. In R. A. Meyers (ed.), Encyclopedia of Molecular Cell Biology and Molecular Medicine, 2nd ed, vol. 8. Wiley-VCH Verlag GmbH & Co., Weinheim. (Review)
  3. Chistoserdova, L.*, Rasche, M.E., and Lidstrom, M.E.  2005.  Novel tetrahydromethanopterin biosynthesis genes discovered via mutagenesis in Methylobacterium extorquens AM1. J. Bacteriol. 187: 2508-2512.
  4. Hamilton, R., Casasús, A., Rasche, M. Narang, A, Svoronos, S. A.*, and Koopman, B*. 2005.  A structured model for denitrifier diauxic growth.  Biotechnology and Bioengineering, 90(4):501–508.
  5. Caccamo, M. A., Malone, C. S., and Rasche, M. E.*  2004.  Biochemical characterization of dihydromethanopterin reductase, a tetrahydromethanopterin biosynthesis enzyme in Methylobacterium extorquens AM1. J. Bacteriol. 186:2068-2073.
  6. Rasche, M. E.*, Wyles, S. A., and Rosenzvaig, M.  2004.  Characterization of two methanopterin biosynthesis mutants of Methylobacterium extorquens by use of a tetrahydromethanopterin bioassay.  J. Bacteriol. 186:1565-1570.
  7. Bobik, T.A., Rasche, M.E.*  2004. Purification and partial characterization of the Pyrococcus horikoshii methylmalonyl-CoA epimerase.  Applied Microbiology and Biotechnology 63 :682-685.
  8. Rasche, M. E.*  2004.  Outcomes of a research -driven laboratory and literature course designed to enhance undergraduate contributions to original research.  Biochem. and Molecular Biology Educ. 32:101-107.
  9. Kima, P.E.*, Rasche, M.E.  2004.  Sex determination using the polymerase chain reaction.  Biochem. and Molecular Biology Educ. 32:115-119.
 
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