X-ray Diffraction Facilities
The x-ray diffraction
laboratory, located in McCarthy Hall of Letters and Science, houses three high-powered
crystallographic systems for powder, small molecule and macromolecular applications that
satisfy the diverse needs of the CSU. Our most recent addition is a Gemini R
with Ruby CCD, dual source enhanced Mo and Cu.
As part of our original configuration, Bruker AXS provided a completely integrated HISTAR area detector/ copper rotating anode system for macromolecular structure determination that can also double as a small molecule diffractometer. The P4/RA diffraction system allows quick and easy switching between small molecule and macromolecule configurations. The 2-theta arm on the P4/RA has a dovetail mount that supports both the area detector and FSD single point detector.
Funding from the W.M. Keck Foundation provided the second piece of instrumentation that made CMolS a truly dedicated facility. The SMART CCD system for small molecule structure determination is furnished with a sealed-tube molybdenum source generator. This detection system provides excellent spatial resolution with the ability to measure very weak and very strong reflections at the same time and rapidly. Both systems are equipped for cryogenic work.
All instruments are remotely accessible and furnished with a
variety of crystallographic software packages for data handing and processing,
structure determination and refinement, and model building. We also provide our
user community with regular access to major synchrotron beamlines for protein
crytallography.